Prof. Benoliel was Chair of the Department of Oral Medicine at Hadassah, Jerusalem 2003-2010. In 1997-1998 he trained at the NIH, USA. In 2013 he moved to the Dental School at Rutgers University as Associate Dean for Research and Director of the Center for Orofacial Pain and Temporomandibular Disorders up till 2021 and is currently Emeritus Professor at Rutgers.

Dr Benoliel has published extensively on the clinical phenotypes of orofacial pain and their interface with headache and continues to publish in both clinical and basic related sciences. His research is focused on identification and management of facial and head pain and at a basic level on trigeminal traumatic neuropathies. He is presently the Editor-in-Chief of the Journal of Oral and Facial Pain and Headache and co-edited the award-winning textbook "Orofacial Pain and Headache”. He serves in many scientific committees including the Classification Committees of the International Headache Society, the joint IASP/WHO classification workforce for chronic pain in ICD-11 and was key in the establishment of the first ‘International Classification of Orofacial Pain’ published in Cephalalgia.